研究成果： |
承担的项目： 国家自然科学基金：磁驱动肿瘤嗜热酶疗的研究 吉林省自然科学基金：高温糖基化生物反应器的构建 国家重点研发计划项目子课题:基于酶和工程菌改造技术的分布式DNA活字存储阵列研究
2021年以来课题组发表文章： [1] Zihao Huang, Yingdan Piao, Xiemuxinuer Abuduwupuer, Simeng Ding, Tian Chen, Song Jiang, Yiqi Ding, Zheng Guo*, Renjun Gao*, Design of a recombinant Pseudomonas strain with enhanced degradation viability towards catecholic compounds by reconstituting EDO-hydrolysis pathway, Journal of Environmental Chemical Engineering, 2025, 13, (5) 118338. [2] Fang Wang, Yuchen Liu, Qikai Dong, Zihan Li, Senrong Liang, Tianyi Zhang, Liangtao Xu* and Renjun Gao*, Catalysts, 2025, 15, 386. [3] Zihao Huang, Deyuan Qin, Xiemuxinuer Abuduwupuer, Luxin Cao, Yingdan Piao, Zhengkang Shao, Liyan Jiang, Zheng Guo*, Renjun Gao*, Regulate catalytic performance by engineering non-regular structure of extradiol dioxygenase: An entrance to bottom strategy. International Journal of Biological Macromolecules, 2024, 281, 136264. [4] Yajing Li, Xinrui Yang, Qi Chen, Yuejun Li, Renjun Gao*, Unlocking industrial potential: phase-transition coimmobilization of multienzyme systems for high-efficiency uridine diphosphate galactose production. Journal of Agricultural and Food Chemistry, 2024,72, 22217. [5] Zihao Huang, Zhenyu Gu, Xiemuxinuer Abuduwupuer, Deyuan Qin, Yuchen Liu, Zheng Guo*, Renjun Gao*, Engineering non-conservative substrate recognition sites of extradiol dioxygenase: Computation guided design to diversify and accelerate degradation of aromatic compounds, International Journal of Biological Macromolecules, 2024, 264, 130739. [6] Fang Wang, Yi Ouyang, Pengfei Zhou, Yan Zhang, Renjun Gao*, Bekir Engin Eser* and Zheng Guo*, NIR-accelerated cascade reaction for degradation of organophosphorus compounds by Au/PTE/ZIF-8: cooperative effect and mechanism, Catalysis Science & Technology, 2024, 14, 3424. [7] Xiuhui Tang, Lijuan Zhang, Mingwang Huang, Fang Wang, Guiqiu Xie, Rui Huo, Renjun Gao*, Selective enhanced cytotoxicity of amino acid deprivation for cancer therapy using thermozyme functionalized nanocatalyst, Journal of Nanobiotechnology, 2024, 22, 53. [8] Lijuan Zhang, Simeng Ding, Xiuhui Tang, Renjun Gao, Rui Huo* and Guiqiu Xie*, The improved antineoplastic activity of thermophilic L‐asparaginase Tli10209 via site‐directed mutagenesis, Biomolecules, 2024, 14, 686. [9] Yajing Li, Qi Chen, Siyao Liu, Lin Deng, Shichao Li, and Renjun Gao*, Efficient one-pot synthesis of uridine diphosphate galactose employing a tri-enzyme system, Journal of Agricultural and Food Chemistry, 2024, 72, 3644. [10] Yiwen Xu, Xiaoran Xuan, Renjun Gao, Guiqiu Xie*, Increased expression levels of thermophilic serine protease TTHA0724 through signal peptide screening in Bacillus subtilis and applications of the enzyme, International Journal of Molecular Sciences, 2023, 24, 15950. [11] Ye Zhou, Jannik Nedergaard Pedersen, Jacob Nedergaard Pedersen, Nykola C. Jones, Søren Vrønning Hoffmann, Steen Vang Petersen, Jan Skov Pedersen, Adam Perriman, Renjun Gao*, and Zheng Guo*, Superanionic solvent-free liquid enzymes exhibit enhanced structures and activities, Advanced Science, 2022, 9, 2202359. [12] Abidan Ainiwaer, Ao Li, Xingwang Zhao, Yujiao Xu, Siping Han*, and Renjun Gao*, Site-specific covalent immobilization of Methylobacterium extorquens non-blue laccse melac13220 on Fe3O4 nanoparticles by aldehyde Tag, Catalysts, 2022, 12, 1379. [13] Abidan Ainiwaer, Yue Liang, Xiao Ye and Renjun Gao*, Characterization of a Novel Fe2+ Activated Non-Blue Laccase from Methylobacterium extorquens, International Journal of Molecular Sciences, 2022, 23, 9804. [14] Yajing Li, Xue Yang and Renjun Gao*, Thermophilic inorganic pyrophosphatase ton1914 from Thermococcus onnurineus NA1 removes the inhibitory effect of pyrophosphate, International Journal of Molecular Sciences, 2022, 23, 12735. [15] Fang Wang, Yuchen Liu, Chang Du and Renjun Gao*, Current strategies for real-time enzyme activation, Biomolecules, 2022, 12, 599. [16] Jiabao Lyu, Jian Zhang, Jingxuan Zhu, Siao Chen, Tao Han, Yan Zhang, Renjun Gao, Guiqiu Xie*, Zheng Guo*, Molecular dynamics simulation guided distal mutation of Thermotoga naphthophila β-glucosidase for significantly enhanced synthesis of galactooligosaccharides and expanded product scope, International Journal of Biological Macromolecules, 2022, 210, 21. [17] Xiaowen Zhang, Zihao Huang, Dan Wang, Yan Zhang, Bekir Engin Eser, Zhenyu Gu, Rongrong Dai, Renjun Gao*, Zheng Guo*, A new thermophilic extradiol dioxygenase promises biodegradation of catecholic pollutants, Journal of Hazardous Materials, 422 (2022), 126860. [18] Li Zong, Yan Zhang, Zhengkang Shao, Yingwu Wang, Zheng Guo, Renjun Gao*, Bekir Engin Eser*, Optimization and engineering of a self-sufficient cyp102 enzyme from Bacillus amyloliquefaciens towards synthesis of in-chain hydroxy fatty acids, Catalysts, 2021, 11(6), 665. [19] Li Zong, Renjun Gao, Zheng Guo, hengkang Shao, Yingwu Wang*, Bekir EnginEser*, Characterization and modification of two self-sufficient CYP102 family enzymes from Bacillus amyloliquefaciens DSM 7 with distinct regioselectivity towards fatty acid hydroxylation, Biochemical Engineering Journal, 2021, 166, 107871. [20] Jiabao Lyu, Renjun Gao, and Zheng Guo*, Galactosyldiacylglycerols: From a Photosynthesis-Associated Apparatus to Structure-Defined In Vitro Assembling, Journal of Agricultural and Food Chemistry, 2021, 69, 32, 8910.
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